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Search Results for " p53 reactivator "

4

Compounds

Cat No. Product Name Synonyms Targets
T24730 Roslin 2 bromide Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2 FAK , p53
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5. Roslin 2 bromide exhibits anticancer effects.
T6954 PRIMA-1 2,2-Bis(hydroxymethyl)-3-quinuclidinone,NSC-281668,PRIMA 1 Apoptosis , Others , Ferroptosis , Autophagy
PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
T41068 P53R3 p53
P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53 R273H. This compound exhibits p53-dependent antiproliferativ...
T79013 SLMP53-2
SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53's transcriptional activity. This...
TargetMol